My friend started a new charity and is asking her circle for donations. But I choose the causes I support carefully and her’s is not one of them. How can I tell her?

However, she sent me a letter in which she requested that I support a nonprofit organization that she actually started and is running -- which I admire, but do not support. What I mean is: I admire that she had the initiative to start the group,

I have a good friend who is the polar opposite of me on politics, religion and almost every other subject. We are cognizant of these differences, and refrain from debate or argument on these subjects.